Introduction Hyaluronic acid (HA) fillers are among the most widely performed minimally invasive aesthetic procedures globally, with over 6.3 million procedures performed worldwide in 2023 . While traditionally used for localized contouring, emerging large-scale data from Japan indicate a paradigm shift toward full-face, anatomy-based rejuvenation —particularly in aging populations. The study by Taichi Tamura et al. (2026) provides one of the most comprehensive real-world da

Introduction Infraorbital hollowness remains one of the most technically demanding indications for hyaluronic acid (HA) filler injection. Despite its apparent simplicity, treatment of the infraorbital groove carries a disproportionately high risk of aesthetic dissatisfaction and vascular complications when anatomical diagnosis is inadequate. Contemporary evidence increasingly supports an anatomy-first, diagnosis-driven approach  rather than a purely technique-based one. Rece

According to Hong, Wong, Yoon, Wan, and Yi (2025), marionette lines, or static labiomandibular folds, are age-related perioral wrinkles extending from the oral commissures to the mandibular border. They can significantly impact facial aesthetics, particularly in Asian populations. Their development is multifactorial, influenced by anatomy, aging, and lifestyle factors. Clinicians need a comprehensive understanding of facial anatomy, wrinkle etiology, and appropriate injection

Lower lip augmentation using dermal fillers has become a cornerstone in modern aesthetic medicine. Patients today seek natural enhancement of volume, symmetry, and definition—but the key to optimal results lies not just in artistry, but in anatomical precision. A recent anatomical study published in the Journal of Clinical Medicine  (Swancutt et al., 2025) provides compelling insights into the vascular structures of the lower lip, reinforcing the need for high-level anatomica

The pursuit of a youthful appearance is universal, and in recent years, combined treatments using hyaluronic acid (HA) fillers and polydioxanone (PDO) thread lifting have gained popularity, particularly for mid-face rejuvenation. This is especially evident in the Asian population, where the primary focus often centers on enhancing the contours and volume of the mid-face. While both HA fillers and PDO threads are effective individually, their combination for long-term rejuvena